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       COMMENT PAGE FOR:
  HTML   Attention lapses due to sleep deprivation due to flushing fluid from brain
       
       
        pedalpete wrote 11 hours 2 min ago:
        This is fascinating, and somewhat directly related to the work we do
        increasing slow-wave response during sleep.
        
        For those who are not aware, slow-wave are the hallmark of deep sleep
        and closely linked to the flushing the glymphatic system, which is what
        they are referring to in this article.
        
        We can't create slow-waves, but we can increase their effectiveness
        through precisely timed auditory stimulation. I'll be posting a Show HN
        next week which dives into the data of how this works, but if you want
        to know more, there is info on our website and links to over 50
        published peer-reviewed papers. [1] This paper specifically looks at
        amyloid clearance as a result of this glymphatic flush [2] While many
        people will point to "getting more sleep" that isn't really the answer.
        More time asleep does not automatically mean increased glymphatic
        flush. Additionally, as we age, the power of the pump gets weaker, and
        more sleep does not help with that.
        
        We believe the focus on counting minutes of sleep misses the point of
        what makes sleep truly restorative and beneficial, which are the
        neurological processes, and downstream physiological changes as a
        result. This is why we talk about restorative function, and that should
        be the focus of sleep health, not time.
        
        After all, you wouldn't measure your diet based on how much time you
        spend chewing, would you?
        
  HTML  [1]: https://affectablesleep.com
  HTML  [2]: https://doi.org/10.1093/ageing/afad228
       
        hyperjeff wrote 11 hours 15 min ago:
        Back when I used to meditate regularly, I would find that an extra
        meditation in the middle of a sleepless night would go a long way
        toward pushing off the need for sleep. Generally, meditating always
        left me in a slightly heightened awake state. Perhaps the help with
        brain fluid regulation is a core reason for both effects. (I should go
        back to meditating again.)
       
        heywoods wrote 11 hours 24 min ago:
        This reminds me of delirium tremens a bit. Same compensatory mechanism,
        different sleep process - or at least that's the pattern I'm seeing.
        
        The MIT study shows CSF waves—normally a sleep-only process that
        flushes metabolic waste—intruding into wakefulness when you're
        sleep-deprived. Your brain is apparently so desperate for the cleanup
        that it forces the process to happen anyway. Cost: attention lapses.
        
        From what I've read, delirium tremens during alcohol withdrawal seems
        to follow a similar pattern, except it's REM sleep intruding into
        waking consciousness instead of CSF flushing.
        
        [Polysomnographic studies from the 1960s-80s]( [1] ) documented this.
        Patients in alcohol withdrawal exhibit what researchers call ["Stage
        1-REM"]( [2] )—a hybrid state where wakefulness and REM sleep
        characteristics get mixed together. Right before full-blown DTs, [some
        patients hit 100% Stage 1-REM]( [3] ). The hallucinations appear to be
        [literally enacted dreams]( [4] ) occurring while technically awake.
        The sleep-wake boundary just completely breaks down.
        
        What strikes me is the system-level similarity here. Sleep normally
        maintains clean states: you're either awake (alert, reality-testing
        intact, no CSF flushing) or asleep (offline, dreams permitted,
        maintenance running). But when the system gets stressed
        enough—whether through sleep deprivation or the neurochemical chaos
        of alcohol withdrawal—it seems to start making desperate tradeoffs.
        
        The brain apparently needs certain processes to run. Period. Total
        no-brainer! CSF flushing can't wait indefinitely. Neither can REM
        sleep, which serves its own critical functions. So when normal sleep
        architecture fails, the system appears to force these processes anyway,
        even though the conditions are completely wrong for them.
        
        Maybe that's why the costs are so specific. CSF intrusion during
        wakefulness costs you attention. REM intrusion costs you reality
        testing, because REM is the state where your brain accepts impossible
        narratives without question. Same compensatory mechanism, different
        critical process forced into the wrong state.
        
        What I find interesting is how the brain knows what lever it needs to
        pull and how it pulls it. Sleep deprivation forces waste removal. REM
        deprivation forces  wakeful dream states; which might be a side effect
        not the actual goal. The brain seems to know what maintenance is
        overdue and attempts the repair, consequences be damned.
        
  HTML  [1]: https://pubmed.ncbi.nlm.nih.gov/7318677/
  HTML  [2]: https://www.sciencedirect.com/topics/neuroscience/delirium-tre...
  HTML  [3]: https://link.springer.com/chapter/10.1007/978-1-4757-0632-1_36
  HTML  [4]: https://www.sciencedirect.com/science/article/abs/pii/S0165178...
       
        handfuloflight wrote 11 hours 24 min ago:
        I can feel when this fluid hasn't properly flushed.
       
        assimpleaspossi wrote 12 hours 7 min ago:
        Maybe unrelated but, years ago, I had a job that had me criss-crossing
        the country by plane Monday through Friday and sometimes Saturday. So
        my sleep and the time zones and hotels could sometimes mess with me.
        
        One day, I went to a grocery store and mid-turn onto another street, I
        forgot what city I was in. Worse, I was half a mile from my apartment
        in my home town.
       
          hollerith wrote 12 hours 5 min ago:
          How long did it take you to orient or to get home (whichever one
          happened first)?
       
            assimpleaspossi wrote 9 hours 6 min ago:
            It was very brief. Only a few seconds
       
        gcanyon wrote 12 hours 51 min ago:
        What I want to know is: can we trigger these flushes? My grandfather
        died of/with Alzheimer’s, and I’d prefer not to follow in his
        footsteps. If we determine that these flushes are key to good brain
        health, and there were a way either through a pill or even a treatment
        to up the frequency of these flushes, that would be awesome.
       
          laptopdev wrote 4 hours 1 min ago:
          Carnivore
       
          Muromec wrote 10 hours 55 min ago:
          I know a reliable way to trigger this. 400 gram of lamb, one bell
          pepper, one or two leek, one zucchini, some random spices (red chili
          pasta from the shop works a-okay), put in  at slow heat for an hour
          and a half, so by 4 in the evening it's ready and you can close your
          laptop. Serve with rice or mercimek chorbasi.
          
          The fluids have no chance to not be flushed once you are done with
          it.
       
          pedalpete wrote 11 hours 8 min ago:
          We can't "trigger" the flushes, however, it looks like we can
          increase the power of the pump.
          
          This is specifically the area we work in traditionally called
          slow-wave enhancement which is stimulating the restorative function
          of sleep.
          
          This paper [1] specifically looks at amyloid response as a result of
          stimulation and shows a corresponding relationship between
          stimulation response, amyloid response, and memory. I wouldn't say
          it's putting a bow on the results, but it is a very promising result.
          
          If you're curious about what we're building, I'll be posting a ShowHN
          next week which dives into some of the data in a way regulatory
          requirements don't permit us to do on our website, but until then,
          check out [1]
          
  HTML    [1]: https://affectablesleep.com
  HTML    [2]: https://doi.org/10.1093/ageing/afad228
       
            amluto wrote 6 hours 39 min ago:
            Why is a headband a subscription service?
       
            hammock wrote 10 hours 58 min ago:
            > We can't "trigger" the flushes
            
            How do you know that?
       
              pedalpete wrote 10 hours 41 min ago:
              I work in neurotech/sleeptech and this is the primary function
              our work focuses on.
              
              However, I also mis-stated that. It is possible to create a
              slow-wave, however only through magnetic stimulation (rTMS), but
              that is not realistic outside of a hospital environment.
       
                hammock wrote 10 hours 18 min ago:
                Ok awesome. Are you saying that because it is an autonomic
                process or some other reason?
                
                You will probably say no but I wonder if those yogis who can
                exert some control over heart rate, blood pressure, and
                breathing pattern might try to target this process as well.
       
                  pedalpete wrote 10 hours 13 min ago:
                  I'm just saying that based on known science. I don't know if
                  anyone has looked at if yogis, etc can control the glymphatic
                  system.
                  
                  What blew my mind when I got into neuro just over 5 years
                  ago, is that the glymphatic system was only discovered in
                  2012!!!! We have SO much to learn about the brain.
       
          HPsquared wrote 11 hours 39 min ago:
          Choosing to sleep more, I guess.
       
        boogieknite wrote 13 hours 15 min ago:
        should have given them a cup of joe while in the fmri to see what
        difference that made
       
        binary132 wrote 13 hours 36 min ago:
        What I’m picking up here is that if I can just get an automated CSF
        circulator installed I won’t need to sleep or get distracted when
        I’m tired.  That was the point of this article, right?
       
        SilentM68 wrote 14 hours 35 min ago:
        That is very interesting. I have a somewhat related issue with sleep
        cycles.
        This issue, waking around 3:00am every morning then not going back to
        sleep until 6 or 7am, is not really a productive sleep cycle. I read
        somewhere that taking a spoon of sugary substance, like Raw Honey, MCT
        or Collagen, before going to bed can replenish the brain of this
        energy, so it becomes easier to fall asleep. I've been trying it with
        two to three spoons of honey, right before hitting the sack to see if
        it can help me fall asleep again. It seems to be having a somewhat
        positive effect as it does not take me too long to go back to sleep.
       
          rsync wrote 10 hours 18 min ago:
          Extremely fine optimizations - like you are describing - only make
          sense after the major, gross actions have already been exhausted.
          
          Do you have a regular, intensive, exercise routine with a good mix of
          aerobic and resistance training?
          
          Don’t buy the fancy high flow air filter if you’re not even doing
          oil changes…
       
        shomp wrote 14 hours 40 min ago:
        In high school a friend of mine told me about "microsleep" and how your
        brain will oscillate into it if you're under-rested.  This would align
        with that theory.
       
        Olshansky wrote 15 hours 21 min ago:
        Need a cron job to flush that cache
       
        kurtis_reed wrote 15 hours 27 min ago:
        Title sucks
       
        HEmanZ wrote 15 hours 33 min ago:
        I hope that the actual medical field starts taking note of this.
        
        My wife still has to work 24 hour shifts with no sleep, performing
        emergency surgeries no matter how long it has been since she slept.
        During residency only a few years ago she and her co-residents were
        almost weekly required to do 36 hour shifts (on top of their regular 16
        hours per day, 5 day per week schedule) and once even a 48 hour shift
        when the hospital was short staffed.
        
        Of course I’m sure they won’t. No one cares if doctors are over
        worked.
       
          evulhotdog wrote 1 hour 9 min ago:
          Current ACGME rules allow a max of 30 consecutive hours, so not as
          bad but still not great for someone you would hope to have fine motor
          skills to save a life!
       
          bmitc wrote 10 hours 1 min ago:
          Were these continual shifts? I thought that doctor's on shift like
          this were given sleep rooms to sleep when they aren't needed.
       
            evulhotdog wrote 1 hour 3 min ago:
            Yeah they usually do have a dedicated sleeping space for their
            service. The thing is, they only sleep if there’s enough
            downtime. Depending on your service, size of the program, and of
            course who your patient population is, it could be a lot, or none
            at all.
       
          whamlastxmas wrote 10 hours 30 min ago:
          This stupid hazing ritual is only happening because of the AMA, which
          is doing it for really stupid "because we had to" logic.
       
          ineedaj0b wrote 12 hours 4 min ago:
          her at her worst is better than 90% of people at their best.
          
          if you get through and into a good med school -match into surgery-
          you are Peak in a way very few are.
          
          I don’t see this changing unless they reduce the requirements for
          med school; if they let anyone in who wants in and force that group
          to work 30hr shifts - you’ll get enough bad outcomes the system
          will change.
          
          There was a study, I believe on nurses and shift durations. The study
          found the nurses were happier with shorter shifts - but the patients
          did worse. Patients come first.
          
          I could see a group of Doctors loudly proclaiming love for Donald
          Trump (and mentioning very much how great he is) and pleading the
          case for a change and something happening. He is an interesting
          president.
          
          I would be interested in hearing a european drs perspective, I heard
          they work shorter shifts (but no EU dr I met has confirmed, it’s
          like meeting a unicorn)
       
            lostlogin wrote 11 hours 25 min ago:
            > her at her worst is better than 90% of people at their best.
            
            A fraction of a fraction of a percentage of people are good at
            surgery.
            
            If I need someone cutting me, I’d prefer someone good, and that
            they were rested.
       
          random3 wrote 15 hours 22 min ago:
          I think both doctors and patients would want a different system for
          both doctors and patients. Having seen a poor performing medical
          system, and comparing it with the US medical system, all I can say
          it's that the US one doesn't seem designed to optimize health and
          well being of patients and, based on reading several articles
          representing doctors opinions, neither doctors'.
          
          I do think it's maximially optimized to extract revenue. That can
          sometimes be good (e.g. good access to healthcare) but often times
          it's not great.
          
          Given healthcare, along with education should be a national priority,
          both should be heavily "configured" to serve peoples' goals first and
          any financial goal should be secondary (although arguably useful).
          
          I suspect the current shareholder structures from hedge funds are
          (intentionally or not) driving things in the wrong direction wrt to
          public health goals. This is article from a few days ago is also
          interesting
          
  HTML    [1]: https://news.ycombinator.com/item?id=45680695
       
          lordnacho wrote 15 hours 29 min ago:
          I've never understood those long shifts. Unless a shift just means
          you are there but sleeping, what is the reason for allowing it? We
          don't let truck drivers do 24h shifts, why do doctors the world over
          seem to do this?
       
            magicalhippo wrote 11 hours 17 min ago:
            Here in Norway the doctor's association have worked hard against
            it, and talking to a relative which became a doctor some years ago,
            it's primarly because they want to keep the extra premium pay they
            get from the "uncomfortable hours" as it's called here.
       
            cma wrote 13 hours 22 min ago:
            The AMA works to prevent importing doctors from other countries,
            largely to maintain wages, but we don't have enough doctors.
            
            Doctors boards and AGME (partly governed by AMA, but there is some
            amount of public representation) control residency admissions and
            board certification.  We don't necessarily want low admissions
            standards, but there is a lot potential conflict of interest in
            constraining supply.
            
            Some states, I think I read Florida recently, have started pushing
            back to allow in foreign doctors.
       
            munificent wrote 15 hours 18 min ago:
            My understanding is that the research shows that the harm to
            patient care from information loss during doctor shift turnover is
            worse than the harm from fatigued doctors.
            
            Yes, a tired doctor sucks. But a tired doctor who already has the
            patient's state loaded into their head may still be better than
            doctor who is completely fresh in both senses.
            
            It's a hard problem.
       
              amluto wrote 6 hours 43 min ago:
              I have never, in my entire life, ever personally encountered a
              situation in which a doctor paid enough attention to anyone over
              a period of time exceeding two hours that I could possibly
              believe that keeping the doctor on shift for a long time had the
              slightest benefit.
              
              I’m sure cases exist. But I’d be rather surprised if
              they’re common.
       
              arcticfox wrote 12 hours 17 min ago:
              > Yes, a tired doctor sucks. But a tired doctor who already has
              the patient's state loaded into their head may still be better
              than doctor who is completely fresh in both senses.
              
              AI fixes this. Imagine the boot time of loading a patient's state
              from dozens of labs and files vs. a summary that gets you to
              exactly what they're going to end up remembering anyways. And if
              a doctor finds something interesting that the AI doesn't flag,
              they should be flagging it in the chart for the next doctor
              anyways.
       
                munificent wrote 9 hours 52 min ago:
                Jesus Christ you have to be fucking kidding me.
                
                Your solution to information loss during doctor handover is to
                insert a brainless  hallucinating program with zero
                responsibility into the middle?
       
                solsane wrote 11 hours 57 min ago:
                In my experience, AI summarization is a pretty lame
                application. I don’t really need a block of potentially
                wrong, rephrased text. I’ve got a feeling that the same
                applies to healthcare.
       
              K0HAX wrote 12 hours 50 min ago:
              Instead of 1 doctor covering a 24 hour shift, why not pair them
              and overlap?
              
              12:00am - 6:00am: Doctor 1 and Doctor 4 are doing everything
              together.
              
              6:00am - 12:00pm: Doctor 1 and Doctor 2 are doing everything
              together.
              
              12:00pm - 6:00pm: Doctor 2 and Doctor 3 are doing everything
              together.
              
              6:00pm - 12:00am: Doctor 3 and Doctor 4 are doing everything
              together.
              
              This way, all 4 doctors only do 12 hour shifts, and the patient's
              state is maintained continuously through all 24 hours.
       
                patcon wrote 7 hours 42 min ago:
                Maybe doctors are divas and they tend to not communicate very
                well with others
       
                janalsncm wrote 8 hours 57 min ago:
                The answer is there’s already a doctor shortage, and the US
                simply does not have the capacity to effectively 2x the
                doctor-patient ratio.
                
                Doctors are also unlikely to want a 50% pay cut in exchange for
                shorter hours. They aren’t directly exposed to the risk
                caused by fatigue since they will have malpractice insurance.
                Therefore the safer method of care would be simply too
                expensive, and doctors wouldn’t see an upside.
                
                Part of the shortage is a result of artificially constrained
                supply as there aren’t enough med school seats to keep up
                with demand.
       
                  IncreasePosts wrote 6 hours 41 min ago:
                  The doctor shortage is entirely caused by intentionally
                  limiting how many doctors are admitted to med school every
                  year
       
                munificent wrote 9 hours 54 min ago:
                Here's an anecdote that might help answer. When my wife was
                pregnant with our first doctor, she started hemorrhaging
                spontaneously ten weeks before her due date. We rushed to the
                ER.
                
                1. Shortly after, a doctor A came in, asked some questions,
                looked at the chart, and told us she was having the baby
                tonight. Holy shit our life is about to get crazy and we're
                going to be parents 2+ months early! He leaves.
                
                2. Several hours later doctor B comes in. We ask about
                delivery. "Oh, no. You're not going to have the baby now. But
                you will have to be on bed rest until the due date." Jesus, my
                wife is going to have to quit her job.
                
                4. Even more hours later, now the next morning, doctor C
                arrives. "OK, you're free to go home. No bed rest needed. Just
                let us know if anything else happens."
                
                My general experience with doctors is that you get as many
                unique opinions as there are doctors in the room. This is not
                an indictment of the profession. Human bodies are insanely
                complex, there is way more variation between them than most
                people realize, and doctors are operating under very very
                limited time and information.
                
                Having overlapping doctors would likely cause even more patient
                confusion and increase the risk conflicting treatments. Also,
                it would obviously double the cost of care.
                
                (My wife and baby were fine. Partial abruption. Very scary and
                my daughter was born five weeks early, but no other significant
                problems.)
       
                  janalsncm wrote 8 hours 59 min ago:
                  Many industries have solved this issue already. Use a
                  pilot/copilot model. First doctor drives, second one mostly
                  observes and makes sure the first one doesn’t make
                  mistakes.
       
                    lostdog wrote 4 hours 40 min ago:
                    Then you'd need to pay more doctors, and it would be much
                    harder for the hospital to make a lot of money!
       
                lostlogin wrote 11 hours 27 min ago:
                That’s a lot of handovers.
       
                someguyiguess wrote 11 hours 56 min ago:
                If engineers ran the world
       
                ineedaj0b wrote 12 hours 0 min ago:
                Doctors do not get along and that’s too many Drs. Each
                patient often has multiple speciality Drs visiting them and
                reviewing their case up to 3 or 4 sometimes already. Imagine
                being on consult and trying to figure out which guy  on a team
                of 4 you should talk to about such and such.
       
              renewiltord wrote 12 hours 57 min ago:
              The European Working Time Directive has requirements for rest,
              etc. Either Europeans have much better hand-off procedures, they
              don't know how to comply with the rules they make, or they're
              fucking idiots who are going to kill people due to information
              loss during shift turnover. It was proposed decades ago. I wonder
              what compliance is like in Germany, etc.
       
              thaumasiotes wrote 13 hours 24 min ago:
              > My understanding is that the research shows that the harm to
              patient care from information loss during doctor shift turnover
              is worse than the harm from fatigued doctors.
              
              This would not appear to apply to emergency surgeries. They
              aren't done by doctors who are familiar with the patient anyway.
              (Neither are non-emergency surgeries. Surgeries are done by
              doctors who do that kind of surgery. Familiarity with the patient
              is useful in deciding what surgery should be done, but not in
              doing the surgery.)
       
              Fire-Dragon-DoL wrote 14 hours 58 min ago:
              What about the harm to the doctor themselves+the harm to the
              patient? Would the sum of both be worse?
       
                arjvik wrote 14 hours 42 min ago:
                One signed up knowing the risk
                
                (not defending, I also think its insane, just devils advocate)
       
              harperlee wrote 15 hours 13 min ago:
              That only works if the mean stay in the hospital (or at least the
              critical care period) is several hours but also way below 24h…
       
                Timon3 wrote 14 hours 35 min ago:
                Longer shifts mean fewer shift turnovers for any patients that
                stay a sufficient amount of time, especially if longer than
                24h.
                
                The world doesn't run on boolean logic. A solution can improve
                an issue without solving it completely.
       
        JumpCrisscross wrote 15 hours 39 min ago:
        Could ADHD be caused by a broken flushing response? Lots of flushing
        followed by intense focus caused by the tabula rasa?
       
          Geee wrote 14 hours 22 min ago:
          Not sure if it's related, but I have way more ADHD-like symptoms if
          I'm on late sleep schedule, but sleeping the same amount of hours.
       
          Citizen8396 wrote 14 hours 47 min ago:
          Disordered sleep can cause executive dysfunction similar to ADHD, but
          it does not cause ADHD. It certainly can exacerbate it or be
          diagnosed incorrectly.
       
          luciferin wrote 15 hours 1 min ago:
          I suppose it's possible, but it seems less likely to me because ADHD
          is a life long neurodevelopmental disorder that shows [visible
          physical changes in the brain on scans]( [1] ).  That said, there are
          statistically more people with narcolepsy who have ADHD, and the same
          goes for sleep apnea.  There's a number of hypotheses I've read as to
          why, to name a couple: related epigenetic causes, or [possible
          misdiagnosis]( [2] ) (narcolepsy is much harder to diagnose than ADHD
          if you don't have textbook symptoms).  So there is definitely
          something there.
          
  HTML    [1]: https://pmc.ncbi.nlm.nih.gov/articles/PMC7879851/
  HTML    [2]: https://pmc.ncbi.nlm.nih.gov/articles/PMC7336577/
       
          delecti wrote 15 hours 16 min ago:
          I'm not an expert, but that wouldn't really fit with my understanding
          of ADHD. It's not that we have a lack of attention ("defecit" of
          attention, as the name suggests), it's an impaired ability to direct
          it.
          
          To abuse a metaphor, the sleep-deprivation-induced spontaneous CSF
          flush is slamming on the brakes of a car, and ADHD related attention
          shifts would be more like a drunk toddler is turning the steering
          wheel wherever they please, but the gas/brakes still work fine.
       
        rickcarlino wrote 15 hours 40 min ago:
        Could this be why SNRIs help some patients mitigate ADHD symptoms?
       
        codethief wrote 16 hours 14 min ago:
        > The scientists found that during these lapses, a wave of
        cerebrospinal fluid (CSF) flows out of the brain
        
        > Lewis and colleagues showed that CSF flow during sleep follows a
        rhythmic pattern in and out of the brain
        
        > Most significantly, they found a flux of CSF out of the brain just as
        those lapses occurred. After each lapse, CSF flowed back into the
        brain.
        
        I can't believe the authors of the article didn't address one of the
        most obvious questions: Where does the CSF flow to and where does it
        flow back from? It's not like there are pipes leading out of the brain,
        or the CSF will just leave my brain through my ears or anything, will
        it?¹ What happens with the waste products? (¹ Though it would be
        kinda funny if this was where snot comes from.)
        
        EDIT: Wikipedia's got the answer:
        
        > Clearing waste: CSF allows for the removal of waste products from the
        brain,[3] and is critical in the brain's lymphatic system, called the
        glymphatic system. Metabolic waste products diffuse rapidly into CSF
        and are removed into the bloodstream as CSF is absorbed.  When this
        goes awry, CSF can become toxic […]
        
  HTML  [1]: https://en.wikipedia.org/wiki/Cerebrospinal_fluid
       
          dragonwriter wrote 16 hours 6 min ago:
          > It's not like there are pipes leading out of the brain
          
          There are, in fact, “pipes” leading out of the brain.
          Cerebrospinal fluid is (and this is probably somewhat oversimplified)
          produced from material in the bloodstream in the ventricles in the
          brain, flows through the system of ventricles and then out of the
          brain into the subarachnoid space around the brain and spinal cord,
          and is then reabsorbed into the bloodstream.
       
            cvoss wrote 14 hours 54 min ago:
            And some people literally need an actual pipe implanted to assist
            with CSF drainage.
            
  HTML      [1]: https://www.mayoclinic.org/tests-procedures/brain-shunt/ab...
       
          svnt wrote 16 hours 8 min ago:
          They didn’t put it in there because knowing the flow of CSF is so
          elemental to performing research in the field that it would be a
          waste of everyone’s time.
       
            codethief wrote 15 hours 37 min ago:
            This is a pop sci article, though?
       
        cozzyd wrote 16 hours 14 min ago:
        As a chronic undersleeper, good thing I don't drive!
       
          fsckboy wrote 4 hours 16 min ago:
          isn't chronic undersleep associated with dementia in old age?
          meaning, whatever you have to do, stop doing that.
       
        gwbas1c wrote 16 hours 15 min ago:
        Sometimes when I get a really bad migraine and poor sleep together, I
        can literally feel a flushing feeling in my head once I can fall
        asleep.
       
        pstuart wrote 16 hours 15 min ago:
        My pet theory is that dreams are the brain booting up/shutting down and
        the equivalent of old analog TVs that have the flash of static and
        bloom/collapse on the screen when turning off/on.
       
        bzmrgonz wrote 16 hours 26 min ago:
        hmm.. this is interesting... the article says "spinal fluid exits the
        cerebrospinal fluid (csf) flows out of the brain... I wonder where it
        discharges these waste products.  I ask because it is believed we have
        a sort of chimney on our backs. I think I read this on the article of
        the Irish lady who could detect alzheimers years before any modern
        medical detection systems.  But maybe it is discharged in the gut? via
        the mesentery, the new organ they finally named fo rthe stuff that
        holds our intestines together.    If anyone knows where it is discharged,
        please comment, I'm interested in this, because I do prolong waterfasts
        every 3 months, and I strongly believe the brain drains waste into my
        mouth during that time, because the taste in my mouth is godawful, but
        if there are other exit points the brain discharges waste, we probably
        need to know about them.
       
          alfonsodev wrote 15 hours 59 min ago:
          What I understood from youtube gurus, take it with a grain of salt,
          is that your  brain is taking ketones as source of energy to preserve
          the little glucose that goes into the system, and as result it
          consumes less oxygen.
          
          But I'm not sure the mouth taste comes from the brain's waste.
          
          To some degree, if you had your brain inflamed by bad eating habits,
          fasting would revert that and make the flushing more efficient as
          well.
          
          Again please take with with double grain of salt, since I don't even
          know inflame brain is a thing for sure, or the correct term.
       
          jp57 wrote 16 hours 10 min ago:
          Why do you think that the taste in your mouth is waste draining from
          your brain and not the result of some metabolic changes in your body
          from the fast?    Ketosis is known to cause a metallic taste in the
          mouth, for example.
       
          canadiantim wrote 16 hours 24 min ago:
          I believe it's discharged basically half directly into the venous
          system in the neck, the other half goes through the
          lymphatic/glymphatic system and ultimately also the venous system in
          the neck. That being said, that's just based on our very crude
          understandings and I'm sure there are other pathways.
       
          kingkawn wrote 16 hours 24 min ago:
          The description of the mesentery as a single organ dates to the time
          of Da Vinci, at the latest.
       
        0xbadcafebee wrote 16 hours 39 min ago:
        So... can we trigger it manually? I'd love to be able to lay down and
        press the 'flush brain' button.
       
          g-b-r wrote 15 hours 31 min ago:
          If you're very tired you should be able to fall asleep, or at least
          doze off, whenever you let yourself go.
          
          It seems likely that you'll get those flushes right after falling
          asleep, so a nap of a few minutes could help a lot.
          
          In my experience, after a night without sleep even a 30 seconds nap
          reinvigorates you significantly.
       
          pbhjpbhj wrote 15 hours 39 min ago:
          Searching back, as I recall a video that was supposed to cause
          [increased] CSF flow, I did find this - [1] about suggestions some 
          learning difficulties might be due to interrupted CSF fluid flow.
          
          The video (?) was related to clearing of plaques from the brain with
          a view to mitigating Alzheimer's effects.
          
          It was not the NSDR (Non-Sleep Deep Rest) videos a sibling commenter
          posted.
          
  HTML    [1]: https://news.ycombinator.com/item?id=34764730
       
            krackers wrote 12 hours 35 min ago:
            
            
  HTML      [1]: https://news.ycombinator.com/item?id=41942775
       
          vrx-meta wrote 16 hours 15 min ago:
          Research on NDSR, I have been using this for days I had to wake up
          without proper rest.
          
          If you have 15m, search this on YT for a guided practice and test it
          yourself.
       
            niwtsol wrote 15 hours 1 min ago:
            Kind of related, but there is a concept of polyphasic sleep - where
            you sleep for small increments throughout the day (like 30 minutes
            every 3 hours). I did it for a bit at a startup thinking we were
            "hacking sleep" and "getting more productive hours out of every
            day!" - It takes awhile to transition to it, but once there, your
            scheduled "sleeps" are insane, 15 minutes, feel like straight to
            REM. The main problem was if you missed on schedule sleep you were
            a zombie.
       
              cestith wrote 14 hours 15 min ago:
              When I worked an overnight shift and lived alone, I got into a
              pattern of 2 to 3 hours a go three times a day. These were after
              work, halfway or so through my personal time, and before work. I
              used these separate times in between sleeps for work, almost
              exclusively for chores, and a dedicated slot for hobbies. I
              started each one refreshed, which was great. It doesn’t
              necessarily work so well when aligning your life with a partner.
       
              tetha wrote 14 hours 32 min ago:
              Yeah, when I was looking into the plausibility and function of
              polyphasic sleep, I stumbled across studies from the US Airforce.
              Their conclusion was similar: In a controlled enviroment, it can
              be spectacular and work really, really well.
              
              However, it is very, very fragile to any kind of interruption, so
              they stopped looking into it.
       
            GavinMcG wrote 15 hours 46 min ago:
            NSDR, rather—Non-Sleep Deep Rest.
       
            BobaFloutist wrote 15 hours 46 min ago:
            I believe you were referring to NSDR (Non-Sleep Deep Rest)?
       
              vrx-meta wrote 8 min ago:
              Yes, thanks for the correction. I need to get some real sleep.
       
              Muromec wrote 10 hours 53 min ago:
              Mixing up acronyms is on brand with sleep deprivation.
       
        epsilonic wrote 16 hours 47 min ago:
        Exogenous ketones (such as BHB salts) are known to help with glymphatic
        drainage in the brain during sleep. I've used them extensively and have
        noticed improved sleep with nearly a doubling of the time spent in REM
        stage.
       
          smith7018 wrote 16 hours 42 min ago:
          Could you go into detail what you take, how much, and when? I could
          always use a little boost for my sleep!
       
            epsilonic wrote 12 hours 19 min ago:
            Sure. When I have a night of poor sleep or anticipate one, I
            usually take 6 grams of BHB salts in the morning on an empty
            stomach. You can work your way up to a maximum of 12 grams, but I
            would advise caution since it can cause diarrhea. I would start by
            buying the cheapest product (nutricost) you can find online; if it
            costs more than $80 for ~300g, then you're probably getting ripped
            off. I noticed that I have very lucid dreams and experience strong
            hypnagogic jerks when I take this supplement.
            
            Here is some literature that I've perused to support my
            experimentation with BHB salts:
            
            1. β-hydroxybutyrate is a metabolic regulator of proteostasis in
            the aged and Alzheimer disease brain
            ( [1] )
            
            2. Refueling the post COVID-19 brain: potential role of ketogenic
            medium chain triglyceride supplementation: an hypothesis ( [2] )
            
            My motivation for pursuing this was protracted sleep disturbance
            from long-covid.
            
  HTML      [1]: https://www.sciencedirect.com/science/article/pii/S2451945...
  HTML      [2]: https://www.frontiersin.org/journals/nutrition/articles/10...
       
        shahbaby wrote 16 hours 54 min ago:
        > For example, what you don't want to do is NOT take amphetamines at
        testing if you had used them to study;
        
        Hard disagree there. If you get any anxiety during the test it's better
        to take it only while studying.
       
          85392_school wrote 16 hours 38 min ago:
          Did you mean to reply to < [1] >?
          
  HTML    [1]: https://news.ycombinator.com/item?id=45772306
       
          lazide wrote 16 hours 41 min ago:
          Huh? Care to explain?
       
        thimkerbell wrote 16 hours 54 min ago:
        [This is one of those article titles that would really benefit from
        adding one more word.]
       
          cvoss wrote 14 hours 46 min ago:
          Or some parentheses. Is "due to" naturally left-associative or
          right-associative? I would have said 'right', which gives the
          unintended reading of the sentence.
          
          Attention lapses due to (sleep deprivation due to flushing fluid from
          brain).
          
          (Attention lapses due to sleep deprivation) due to flushing fluid
          from brain.
       
        earless1 wrote 17 hours 19 min ago:
        So biological garbage collection pauses then? skip sleep, and the brain
        tries to run gc cycles during runtime. Causing attention and
        performance latency spikes. Evolution wrote the original JVM.
       
          apatheticonion wrote 5 hours 6 min ago:
          This is a hilarious comment, I actually laughed out loud
       
          hinkley wrote 10 hours 14 min ago:
          Skip enough sleep and parts of your brain will try to nap while
          you’re doing things like meetings.
       
            timeinput wrote 9 hours 13 min ago:
            Depending on the meeting it might be worth a nap even if I'm well
            rested.
       
              jama211 wrote 2 hours 25 min ago:
              That’s every meeting I’m in that contains more  people than
              myself and two others.
       
              hinkley wrote 8 hours 17 min ago:
              But in that cause you are well aware that you have invested no
              brain at all instead of investing half a brain while thinking
              you’re engaged.
       
          dathinab wrote 10 hours 55 min ago:
          this might explain how "power napping" (<30min) can help so much when
          you are sleep deprived even through it's too short to really count as
          sleep. I wonder if you can find that when sleep deprived people power
          nap a "flush" happens then
       
            hinkley wrote 10 hours 10 min ago:
            There’s a phenomenon we have known about since at least the late
            1980s when Race Across America riders were using it.
            
            Essentially these guys try to stay up for the first few days and
            then sleep less than 8 hours after that. Way less. Many of them end
            up hallucinating by the end, and only their extreme fitness levels
            probably save them from just dying from lack of sleep.
            
            The trick is that waking up to daylight makes you feel more rested.
            So the teams would have their riders sleep 2-3 hours from just
            before dawn until dawn so they would wake up to sunlight.
            Physiologically the difference is small, but psychologically it’s
            much bigger.
            
            Some of the effect of power napping is likely the same sort of
            trickery, just as caffeine is partly trickery and partly adrenal.
       
              ra wrote 5 hours 59 min ago:
              I used to do adventure races of 24 or 48 hour duration. can
              confirm that after 20+ hours of endurance you 100% start having
              microsleeps and hallucinations. 20 mins sleep is all you need to
              get going again for a few more hours.
       
                hinkley wrote 41 min ago:
                Seen any pink elephants?
       
          Zenul_Abidin wrote 16 hours 15 min ago:
          Is Sun Microsystems in the room with us?
       
          layer8 wrote 17 hours 12 min ago:
          Luckily it doesn’t clear all unreferenced memory, though.
       
            ghurtado wrote 15 hours 55 min ago:
            I realize you're making a joke, but there is no such thing as
            "unreferenced memories", as in, something that is no longer in use
            and has been removed from the brain.
            
            Every memory your brain has ever produced is still there, even if
            most are beyond conscious access. Memories quite literally become a
            permanent part of you.
            
            A lot of people mistakenly think of human memory as a sort of hard
            drive with limited capacity, with files being deleted to make room
            for new ones. It's very much not like that.
       
              lux_sprwhk wrote 15 hours 24 min ago:
              I had this experience at Big Bend State park that makes me think
              they are. I didn't bring enough water and camped in the primitive
              area. At night, I was dehydrated pretty bad. When I finally got a
              little sleep (it was tough to say the least), I had this vivid
              dream where I put a pebble in my mouth and started sucking on it
              to make saliva. Then I woke up for real, and I knew it because
              there was a lot of wind IRL, that wasn't in the dream. So I took
              out a coin from my back, put it in my mouth to make saliva, and
              got a little bit of relief. Enough for a couple hours until it
              was dawn, and had enough light to hike down to the restroom area.
              
              I don't know where I got this trick. Likely some survival show or
              some novel. But I don't have any background in survival,
              otherwise, I would have brought a lot more water.
              
              So my brain knew there was a memory that could help and made up a
              dream about it is my theory.
       
              vanviegen wrote 15 hours 33 min ago:
              Bullocks. Memories fade. Or do you really believe that
              'subconsciously' I still know what I had for dinner today exactly
              30 years ago?
              
              The way I understand it, it's just that, unlike on disk, the
              deletion process is not binary. Weak connections that are not
              revisited regularly gradually become weaker, until they're
              undistinguishable from noise (false memories).
       
              mym1990 wrote 15 hours 40 min ago:
              Knowing almost nothing about memory and the brain, I don't know
              if I agree with "Every memory your brain has ever produced is
              still there".
              
              Memories seem to be constructed by a group of neurons together,
              and it seems clear that neurodegeneration is a thing, whether by
              trauma or due to aging. When pathways degenerate, maybe you have
              a partial memory that you brain can help fill the gaps with(and
              often incorrectly), but that does not make it the original
              memory.
       
              pdonis wrote 15 hours 52 min ago:
              If you are implying that human memory has infinite capacity,
              that's not possible. The human brain is a finite, physical thing.
              It can't store an infinite amount of data.
              
              If you just mean that human memory has a finite capacity that's
              much larger than anyone has come close to reaching by storing the
              memories of a normal human lifetime, that might make sense.
              
              Do you have any references for your statements about memory? I'm
              not familiar with whatever science there is in this area.
       
                jjk166 wrote 13 hours 39 min ago:
                The claim that everything is there does not imply infinite, or
                even large capacity.
                
                Consider an exponentially weighted moving average - you can
                just keep putting more data in forever and the memory
                requirement is constant.
                
                The brain stores information as a weighted graph which
                basically acts as lossy compression. When you gain more
                information, graph weights are updated, essentially compressing
                what was already in there further. Eventually you get to a
                point where what you can recall is useless, which is what we
                would consider forgotten, and eventually the contribution of a
                single datapoint becomes insignificant, but it never reaches
                zero.
       
                  balex wrote 37 min ago:
                  And this description is based on what?
       
                  pdonis wrote 12 hours 43 min ago:
                  > The claim that everything is there does not imply infinite,
                  or even large capacity.
                  
                  It implies enough capacity to store everything. But what you
                  describe is not storing everything.
                  
                  > lossy compression
                  
                  Which means you're not storing all the information. You're
                  not storing everything.
                  
                  > When you gain more information, graph weights are updated,
                  essentially compressing what was already in there further.
                  
                  In other words, each time you store a new memory, you throw
                  some old information away.
                  
                  Which the person I was responding to said does not happen.
       
                standardly wrote 14 hours 57 min ago:
                > The human brain is a finite, physical thing. It can't store
                an infinite amount of data.
                
                True, but it doesn't really detract from his statement because
                do we really know what that upper bound even is? I don't think
                we come close to the theoretical storage limit... So saying
                "every memory you have is permanently stored" is effectively
                true, at least true enough for a thought experiment like this.
                Perhaps when people live to be 200 years old and we know more
                about the brain we can test this, though.
                
                I used to be weary of learning new, complex things, thinking
                I'd "lose" old knowledge XD
       
                  pdonis wrote 12 hours 46 min ago:
                  > I don't think we come close to the theoretical storage
                  limit
                  
                  That was the point of the second part of my comment--which
                  the person I was responding to said was not relevant to what
                  he meant.
       
                ghurtado wrote 15 hours 37 min ago:
                I didn't mean either of the things that you are wondering
                whether I meant, so i can't give you evidence of those things
                you made up yourself.
                
                If you have questions about my comment, I'm happy to try to
                explain myself better
                
                "I didn't understand you at all, so you must have meant either
                A or B" is not the way to reach an understanding
       
                  pdonis wrote 14 hours 48 min ago:
                  > i can't give you evidence of those things you made up
                  yourself.
                  
                  I didn't ask for that. I asked if you have references for
                  what you said. Even if I misunderstood you, that shouldn't be
                  a reason for you not to give references for your statements,
                  if you have them.
                  
                  If you don't have any references to back up your statements,
                  then I'm not sure what you're basing them on.
       
                  vanviegen wrote 15 hours 30 min ago:
                  Your words: "Every memory your brain has ever produced is
                  still there [..]"
                  
                  How would that not imply infinite storage?
       
                    dragonwriter wrote 14 hours 39 min ago:
                    It wouldn't imply infinite storage because human life is
                    not infinite in time and memories do not accumulate at an
                    infinite rate in storage consumed per unit time, so the
                    total storage over a human lifespan is finite, so the claim
                    can be true with finite storage.
                    
                    It is almost certainly false, but it doesn't require
                    infinite storage to be true.
       
                      pdonis wrote 12 hours 45 min ago:
                      > human life is not infinite in time and memories do not
                      accumulate at an infinite rate in storage consumed per
                      unit time
                      
                      Which would put it into the category of the second part
                      of my comment--which the person I was responding to said
                      was not relevant to what they meant.
       
            blauditore wrote 16 hours 35 min ago:
            Fun fact: Suppressed/hidden/lost memories due to trauma that appear
            to re-surface through therapy are not a real thing, as previously
            thought (and still by some psychotherapists). Nowadays it's
            understood by psychology that any memories "re-surfacing" in
            therapy are in fact newly created, although the patient themselves
            cannot tell the difference. Allegedly, whole accusations of
            childhood abuse may have been created out of thin air, without the
            victim realizing. [1] (see research section)
            
  HTML      [1]: https://en.wikipedia.org/wiki/Recovered-memory_therapy
       
              layman51 wrote 11 hours 27 min ago:
              This idea of unconscious memories perhaps being a type of fantasy
              is also discussed in this article too:
              
  HTML        [1]: https://en.wikipedia.org/wiki/Freud%27s_seduction_theory
       
              bozhark wrote 12 hours 22 min ago:
              Careful with this absolute assumption.    The brain rationalizes.
              Though irrationally.
              
              Sometimes yes, created to validate, sometimes no, unlearns to
              disassociate
       
              agumonkey wrote 13 hours 30 min ago:
              I beg to differ, or at least I'd need clarification, some people
              experience traumatic visions from what is assumed repressed
              memories (with or without therapy)
              
              It might be something that one might not understand if he/she
              doesn't live through it I guess
       
              pcthrowaway wrote 14 hours 16 min ago:
              Sure it's a real thing for memories to surface that were
              previously buried. It's happened to me.
              
              If it happens in therapy, that doesn't mean the memories are
              "implanted". And not all memories lack the ability to validate
              them... for example, if you've forgotten someone's name, then
              remember it later, you can call out to them by their name to
              confirm that you've correctly remembered it.
              
              Memories tumble around in the brain all the time, not all
              memories are easy to access, but that doesn't mean they're
              inaccessible.
              
              The point that memories can also be implanted or fabricated
              during therapy is absolutely an important one, but dismissing the
              possibility for memories to resurface (and conflating any
              situation where this might happen with a specific type of
              discredited therapy) is needlessly reductive.
       
              dbspin wrote 14 hours 38 min ago:
              The problem is not that memories can't be repressed. There's
              plenty of research demonstrating repression does exist as a
              defence mechanism. The problem is that even highly evocative
              memories can also relatively easily be falsified, or modified
              through elicitation and reframing. Since there's no neurological
              stenographer, there is no mechanism even in principle to identify
              the difference between the two. With potential consequences like
              the satanic panic of recovered and elicited memories of sexual
              abuse. That's what Elizabeth Loftus and others have shown, and
              shown so thoroughly that eye witness testimony should never be
              trusted.
       
                saltcured wrote 14 hours 10 min ago:
                As a counterpoint to this, I am replying here because I can't
                make myself write a polite response to the GPP.
                
                Yes, witness testimony is always potentially flawed.
                
                But knowing "some repressed memory recovery is false" does not
                justify saying that repressed memories are not a real thing.
                Repressed memories do happen. They do come back sometimes. When
                they do, they are just as valid as any normal memory that a
                person thinks they always had.
                
                I know because I had them myself. Mine were of trauma in the
                age range from 5-9. I had a high "ACE score" when I eventually
                looked into this. I did not have any therapy session prompting
                the recall, I just remembered them spontaneously around age 15
                when I was empathizing with a schoolmate who told me about
                domestic violence. It was a sickening feeling to have this
                whole phase of my past come unlocked.
                
                Amazingly, it submerged into repression again. I next
                remembered it at about age 20. In between, I had years of
                basically not remembering/knowing that I had any of this trauma
                or that I had experience the earlier recall. They all came back
                together, again triggered by an empathetic moment in college.
                Again it was disorienting to have this whole aspect of my past
                reopen.
                
                At that later point, I confronted people who were around my
                childhood and got enough of a painful discussion, confession,
                and apology to know that these memories were not invented.
                
                I had other forms of childhood trauma that never submerged. I
                don't know why this one section did.
                
                I find it very offensive for someone to make broad statements
                that these phenomena do not exist.
       
                  JohnMakin wrote 10 hours 7 min ago:
                  Thanks so much. I was wanting to write a scathing response as
                  well but you calmly explained what I wanted to. I had severe
                  childhood abuse that was documented by third parties I’d
                  completely forgotten about - when I  remembered them in
                  therapy, my therapist thought they were fake or delusional
                  too and sorta gaslit me about it. I had to go hunt down the
                  receipts, which for me was traumatic in and of itself and
                  permanently severed a few relationships with my family
                  members, which didn’t have to happen. I fired her over it.
                  
                  The comments in this thread are indeed disturbing. Clearly
                  many on this forum have led blessed lives and can’t imagine
                  people having it differently,
       
                  oceanplexian wrote 10 hours 27 min ago:
                  You might "think" you had a repressed memory but it could all
                  be completely made up. You might even get other people to
                  believe it, because human memory is incredibly faulty. Shared
                  delusions are literally a "known bug" of human biology.
                  Wikipedia has a whole page on them ( [1] ). The Seattle
                  Windshield Pitting Epidemic ( [2] ) is yet another example
                  
                  The thing that changed though is since the 2010s everyone has
                  a high definition camera in their pocket. Everything you do
                  is recorded online. Kids that grew up in the last few years
                  will have their entire childhood recorded in some way or
                  another. Every movement tracked by GPS. Therefore, while I
                  don't agree completely, I wouldn't be surprised if some
                  assumptions about psychology are upended and a great deal of
                  so called repressed memories turn out to be bogus when we can
                  easily disprove them.
                  
  HTML            [1]: https://en.wikipedia.org/wiki/Folie_%C3%A0_deux
  HTML            [2]: https://en.wikipedia.org/wiki/Seattle_windshield_pit...
       
                    JohnMakin wrote 10 hours 6 min ago:
                    The person you’re responding to said they did the work of
                    verifying themselves with third parties. Do you not believe
                    that too? People dont suddenly just admit to committing
                    severe abuse because they were convinced to do so. In fact,
                    usually the opposite happens with abusers - they delude
                    themselves into thinking the abuse never happened and
                    believe/defend this very aggressively.
                    
                    This whole thread is gross. I’d say you should be ashamed
                    of yourself but you likely lack the prerequisite self
                    inspection.
       
                    saltcured wrote 10 hours 17 min ago:
                    Malicious suppression and gas-lighting are also known
                    functions of human biology.
                    
                    Yes, real life is messy and ideals like justice are quite
                    difficult or impossible to achieve.
                    
                    Don't assume you can cleverly deduce a nice, absolute and
                    comfortable answer. That's just another coping mechanism
                    called rationalization.
       
                  mrsvanwinkle wrote 11 hours 11 min ago:
                  Thank you so much, the parent thread was truly an
                  uncomfortably disturbing read and your post is a necessary
                  contrast to "rational" "objective" "minds" armchairing
                  something so delicate with gross finality.
       
                  eiginn wrote 12 hours 52 min ago:
                  This mirrors my experience as well of multiple instances over
                  my life of repressing childhood trauma and some event or
                  conversation suddenly bringing it back to the surface.
       
                    jimmaswell wrote 12 hours 19 min ago:
                    Not to minimize your experience or anything like that, I'm
                    just thinking out loud: What's typically the delineation
                    between repressed and "not on the mind at the moment"? We
                    naturally "forget" things all the time because there's no
                    need for them to be in our current context window, e.g. I
                    can't recite every coffee shop I've been to, but maybe if
                    you start talking about a coffee shop with uncomfortable
                    seats, I'll remember the one I went to with uncomfortable
                    seats. Not a comparable experience in general of course,
                    but one wouldn't say I repressed the coffee shop. Is it
                    more like if I started at "uncomfortable coffee shop",
                    nothing came to mind, but then I later remembered only
                    after smelling some special flavor of coffee beans they had
                    had?
       
                      JohnMakin wrote 8 hours 19 min ago:
                      IME for me repressed is “not on the mind at the
                      moment” but like so constant that any attempt to access
                      it, your subconscious fights to divert your attention
                      from it. it’s kind of like dim stars you can only see
                      out of the corner of your vision.
                      
                      the craziest one I had, my reaction wasn’t “oh my god
                      i never knew i had this memory” it was “wow, i cant
                      believe i havent thought about that in 25 years.” I
                      knew and had known it was there all along, I just
                      literally never thought of it to the point my other
                      thoughts just didnt collide with it, ever. It’s almost
                      like your brain just puts it in storage in a dark corner
                      of your garage.
                      
                      I understand it isn’t the same for everyone, but that
                      was how it felt for me.
                      
                      TLDR for me it was dissociation, and the only treatment
                      that ever worked was scraping the corners of my mind for
                      stuff like this and it got so much better the issues
                      basically went away. I used a great deal of meditation,
                      particularly tibetan buddhism.
       
                      saltcured wrote 10 hours 26 min ago:
                      A repressed memory and its associated knowledge and
                      entailment is "not there" until triggered properly. To
                      the extent that our autobiographical memories construct
                      our sense of identity, repressed memories have been
                      censored from ourselves. And, I think it is censored for
                      a purpose, not because it was one too many bits of trivia
                      to keep in ready memory. I think it is a coping mechanism
                      like very deep and targeted denial or dissociation.
                      
                      When such memories come back, it can be like a mini
                      identity crisis. You suddenly know things that are
                      counter to your self-identity from the moment before.
                      Once I was able to absorb the whole picture and not
                      recoil back into repression, it became a permanent and
                      unpleasant part of my self. .
                      
                      There can be flashbacks of related events, some of which
                      I also might feel are remembered for the first time in a
                      long time. Those little flashbacks might be like
                      remembering your specific uncomfortable cafe. The overall
                      memory recovery is like suddenly realizing I spent years
                      in a theater of war, that happened to have such cafes in
                      it.
       
                      mrsvanwinkle wrote 11 hours 5 min ago:
                      I can objectively say your reply minimizes the previous
                      two posts who shared childhood traumas by the objective
                      fact that you are implying (if they are not able to
                      satisfy your Scientific Endeavor) that, if there is no
                      delineation, then their repression of childhood trauma is
                      equivalent and minimized or perhaps exalted if coffee is
                      your religion to the repression of your religious
                      experience of this coffee shop. If you were perhaps a
                      child victim in this coffee shop maybe? You literally
                      erased the trauma part. That is the delineation if you
                      still need to think about this out loud
       
              DiscourseFan wrote 14 hours 40 min ago:
              There are two types of repression, however. The notion that
              primarily repressed memories--say, those of being breastfed, of
              being potty trained--could ever resurface is bogus of course. But
              it is that original violence, first of being cared for, and then
              having that care taken away and even, in many cases, transforming
              into authoritarian violence in order to be socialized properly,
              that precipitates all other "secondary" repressions like Freudian
              slips, even screen memories or rationalizations. No, most people
              traumatized past the age of say, 5, won't readily forget it. But
              perhaps they will have a way of reconciling with that trauma in
              an unhealthy or not fully conscious manner (consider
              self-harming, or drug abuse, making up a narrative in order to
              stay with a partner who violently abuses them). And they will not
              readily connect their traumatic experiences with their unhealthy
              coping mechanisms. And we could say that the connection between
              unconscious behaviors and trauma, when revealed, could be
              considered a "re-surfacing." Even if I can't remember being
              breastfed, I know that I find the warm embrace of another's arm's
              comforting and soothing, and this perhaps relates to my original
              state of relaxation as a child in my mother's arms, for instance.
       
                drdeca wrote 9 hours 26 min ago:
                Why would it relate to your past experience of being held in
                your mothers arms, rather than to whatever inbuilt tendencies
                that lead one to respond well to being held in one’s
                mother’s arms while a baby?
                
                Like, if kissing is derived from impulses relating to
                breastfeeding (which is a hypothesis that, AIUI, is in good
                standing, though not the only one in good standing nor
                necessarily more favored than a couple others), I wouldn’t
                think that therefore someone who was only ever bottle-fed as a
                baby would therefore not get anything out of kissing. The
                appeal of “my lips on another person” should be there
                regardless, just as it was for the first time a baby is
                breastfed (though, of course, it is also a cultural thing: not
                all cultures have had kissing as a standardized way of
                expressing affection, so whether one grows up in a context
                where kissing plays a role, that probably also plays a part in
                whether one finds it appealing to have one’s lips on another
                person).
       
              ghurtado wrote 15 hours 47 min ago:
              > any memories "re-surfacing" in therapy are in fact newly
              created,
              
              You're saying that those memories are exactly the same as all the
              other memories.
              
              Every time you "recall" something, you are not pulling up some
              file that is always the same. You are actively recreating the
              memory.
              
              There's nothing "fun" or insightful about this, this mechanism
              has been known for a long time.
              
              Obviously it's not unique to psychotherapy.
              
              > may have been created
              
              Most things that "may" have happened do not warrant absolute
              statements such as "that's not a thing" (which, incidentally, is
              a particularly empty statement in any context, since every thing
              is a thing)
       
              elmomle wrote 15 hours 57 min ago:
              The statement "there is evidence of black swans" does not justify
              the conclusion "every swan is black".
       
                fsckboy wrote 15 hours 38 min ago:
                if you specialize in looking for black swans, and you've looked
                for more black swans than anybody ever, and all the black swans
                you thought you'd found have turned out to be sooty white
                swans, people might be interested in reading about your
                experience and have their faith shaken that black swans
                actually exist.
                
                I'm reminded of the story of dragon sightings in Great Britain:
                after the printing press and newspapers and newspaper reporters
                chasing stories emerged, as news distribution out from city
                centers into rural areas increased, it seems dragons picked up
                and moved farther away, only being spotted in the hinterlands
                without news.
                
                You apparently would keep your mind open to the idea that
                dragons don't like the smell of newsprint as no other
                conclusion could be more plausible sheerly on the basis of
                logic?
       
                  musicale wrote 4 hours 22 min ago:
                  Dragons are smart, and wary of human civilization. They still
                  remember St. George and his ilk.
       
              bollocks9 wrote 16 hours 9 min ago:
              What about Dr. Jim Tucker’s two child psych cases, James
              Leininger and Ryan Hammons?
              
              One remembered memories of a WWII pilot named James Huston Jr.
              and the other a deceased Hollywood agent named Marty Martyn.
              
              Putting aside the reincarnation hypothesis for the moment, do you
              think the kids invented the details and coincidentally happened
              to match to a real person or were they fully coached? Maybe they
              didn’t get enough sleep or got too much sleep?
       
              anal_reactor wrote 16 hours 11 min ago:
              Most people think that when their memory fails it's just the act
              of not remembering something, but misremembering something
              happens equally often, and completely making up shit also does
              happen. It's just like LLM hallucinations.
       
              layer8 wrote 16 hours 19 min ago:
              People can remember things that hadn’t re-entered their mind
              for decades. It certainly happened to me a number of times
              (completely trauma-unrelated and not actively elicited).
       
                GuB-42 wrote 15 hours 0 min ago:
                This is a more precise statement than just "you can recall
                things you thought you forgot".
                
                It is specifically about trauma, and generally you don't forget
                traumatic events and that's often a big part of the problem. We
                are not talking about trivial things like the name of your
                maths teacher in high school, which have a tendency to come and
                go.
                
                It is also specifically about therapy, that is an environment
                where you are actively encouraged to recall memories. We know
                how easy it is to make up memories, especially with the help of
                a third party (here, the therapist).
                
                Combine the two: memories that are hard to forget and an
                environment conductive to making false memories and it becomes
                very likely that the "lost" memories are completely made up.
       
                  Muromec wrote 11 hours 11 min ago:
                  >It is specifically about trauma, and generally you don't
                  forget traumatic events and that's often a big part of the
                  problem.
                  
                  Oh, of course you can.
       
                  theshackleford wrote 11 hours 33 min ago:
                  > and generally you don't forget traumatic events
                  
                  That depends on how many you endured really. Only so much
                  room in the old noggin with everything else important going
                  on.
       
                kulahan wrote 15 hours 15 min ago:
                They won't remember it accurately anyways, so it's kind of a
                moot point.
                
                Though you're right - a specific scent can easily call up an
                ancient, forgotten memory.
       
                Aurornis wrote 15 hours 37 min ago:
                A valid memory spontaneously re-entering your mind is
                different.
                
                The idea of "repressed memories" was that people had hidden
                memories that they couldn't access, even if they tried.
                According to the theory, even if someone brought up the past
                event and tried to remind the person about it, they would be
                unable to recall it happening because their brain had blocked
                it out.
                
                The idea was that only intervention by a therapist or some
                other special event could help the person "unlock" the
                repressed memories, making them available for remembering
                again.
                
                What was really happening was that some therapists were leading
                people into "remembering" things that didn't happen through
                aggressive prompting and pushing, much like what happens when
                an aggressive investigator convinces a vulnerable person to
                falsely confess to something they didn't do.
       
                  tehjoker wrote 15 hours 17 min ago:
                  I wouldn't be surprised if there are inaccessible, partly
                  corrupted memories encoded in the hippocampus. I suspect most
                  of them cannot be prompted by a therapist though, and likely
                  there is no practical way to recover them.
       
                    strbean wrote 15 hours 7 min ago:
                    I think it's all a matter of finding a trigger (or
                    reference) to grab the memory. A therapist talking to you
                    almost certainly wouldn't achieve that, but walking down
                    the street and smelling an odd smell might.
       
                      rkhassen9 wrote 14 hours 8 min ago:
                      I once found a recording of a lab session in high school
                      physics. A day I completely forgot about. A moment that
                      had no bookmarks in my brain.
                      
                      Other things about that day were surfaced. How my braces
                      felt and the fear I felt about forgetting a textbook.
                      
                      All real, but unsurfaced until then.
       
                        t0mas88 wrote 10 hours 24 min ago:
                        That makes sense considering that human memory is
                        strongly based on associations. Activating nearby
                        memories can bring things back.
                        
                        If you hear the first tones or words of a song you're
                        much more likely to be able to tell the lyrics that
                        follow compared to being asked to say those lyrics
                        based on the title.
       
                      tehjoker wrote 14 hours 10 min ago:
                      I think it depends on the stage of degradation and
                      whether the network is still connected to something that
                      can interpret it.
       
                warmedcookie wrote 15 hours 51 min ago:
                Indeed. I was browsing a Nintendo fan site I made in 1998 on
                archive.org when I was just 11 years old. I don't remember
                every detail about making it, but my brain had no problem
                stitching all the pieces it did retain back together.
                
                On the other hand, I do have some Gandalf "I have no memory of
                this place" moments for other things.
       
                worldsayshi wrote 16 hours 9 min ago:
                My guess is that long term memory recovery is inherently a
                reconstruction from the pieces that you have retained. So it is
                not unlikely to include dreamed up parts.
       
                  bpj wrote 14 hours 51 min ago:
                  This has been my experience as someone who has experienced
                  childhood trauma, and what I've inferred from my therapist.
                  He taught me that the memories I have are typically
                  exaggerations of what happened and it's hard to pin down what
                  truly happened. The only evidence I have that has any merit
                  is my siblings can corroborate with similar experiences since
                  it happened to all of us, and I'm sensitive to things related
                  to these traumas. Almost every day I can feel the things that
                  happened, and on my worst days these areas are much more
                  sensitive.
                  
                  On top of that, I have legitimate memories that were not
                  traumatic, but still related to the same traumas because said
                  person attempted to encourage these activities throughout my
                  young life on rare occasions. I didn't remember what happened
                  as a kid, but I knew something wasn't right and I wasn't
                  comfortable. It wasn't until I was almost 30 that I had my
                  first "flashback" which was a fractured memory, I still
                  remember it looked like a faded photograph in my mind, and it
                  was accompanied by an extremely uncomfortable feeling.
                  
                  The re-surfacing memories aren't real in a sense, but in my
                  case they aren't entirely fake either.
                  
                  I wonder if it's possible that things can be completely
                  imagined with absolutely no basis what-so-ever in certain
                  circumstances, and I also wonder how difficult it is to
                  discern that. It seems to be a difficult concept to manage.
       
                  Aurornis wrote 15 hours 21 min ago:
                  The debunked recovered memory therapy was something
                  different: They would use different techniques and leading
                  questions to try to get a patient to think they remembered
                  something that may not have happened at all.
                  
                  Some of the techniques included hypnosis or even giving the
                  patients (including children) sedative-hypnotic drugs before
                  pressuring them with the leading questions.
                  
                  If they could eventually get the person or child to claim to
                  have some memory of the event (after asking a lot of leading
                  questions and maybe even drugging them) they considered it to
                  be a recovery of the memory.
       
                  layer8 wrote 16 hours 1 min ago:
                  The accuracy of recollection can certainly vary, but the
                  point is that some information is retained long-term even
                  when it isn’t made use of in the meantime. Of course one
                  could argue that actually it is being made use of
                  unconsciously, but I’m skeptical of that, given the
                  relative irrelevance of the details that can be recollected.
                  It’s also not that difficult to imagine that some
                  memory-representing micro-structures in the brain just happen
                  to be stable over decades even when they remain untapped.
       
              slater wrote 16 hours 33 min ago:
              Gonna need some citations on that “fun fact”
       
                ghurtado wrote 15 hours 42 min ago:
                People downvoting a request for supporting evidence is peak
                Hacker News.
       
                  fsckboy wrote 15 hours 23 min ago:
                  people demanding supporting evidence without expending any
                  effort themselves is peak internet.
       
                    theshackleford wrote 11 hours 29 min ago:
                    It’s not my job to track down proof only every bullshit
                    claim thrown at me.
       
                    jjk166 wrote 13 hours 53 min ago:
                    The onus of proof lies on those making a claim. If you're
                    unwilling to back up what you say, don't say it.
       
                      fsckboy wrote 3 hours 18 min ago:
                      on a discussion board? no, there is no onus of proof,
                      because nothing is riding on it, just as you don't need
                      proof to reject the ideas.
                      
                      demanding citations is the favorite trick of people who
                      want to waste your time precisely because they disagree
                      with you and no matter what you come up with, they'll
                      never give in. therefore, one should never give in to it.
                      
                      rather, doing your own research and contributing it to
                      the discussion is the lifeblood of online communities.
       
                      nwienert wrote 9 hours 12 min ago:
                      In science. On a casual forum you have no obligation and
                      I’d rather someone leave a short comment so I at least
                      know, if I’m interested I’ll go look and verify
                      myself.
       
                blauditore wrote 16 hours 29 min ago:
                 [1] (especially the research section)
                
  HTML          [1]: https://en.wikipedia.org/wiki/Recovered-memory_therapy
       
                  ghurtado wrote 15 hours 43 min ago:
                  Claim: "modern cancer research is a scam"
                  
                  Proof: "colloidal silver has been used to attempt to cure
                  cancer".
                  
                  Solid logic.
       
                  svnt wrote 16 hours 11 min ago:
                  That is extremely weak to nonexistent counter-evidence that
                  seems to focus on supporting Loftus, who has put a lot of
                  effort into the defense of her public persona. I don’t
                  disagree that it is possible to manufacture memories but the
                  evidence isn’t there to support your conclusion or the
                  converse.
       
                    Aurornis wrote 15 hours 23 min ago:
                    Recovered-memory therapy (the topic of the Wikipedia
                    article) is very clearly quack science and has been
                    discredited.
                    
                    Some of the techniques used in the therapy include giving
                    patients sedative-hypnotic drugs to put the patient in a
                    waking dream-like state while the therapist asks leading
                    questions to get them to "remember" an event. The same
                    drugs they used are known to be associated with false
                    memories, like when someone falsely recalls something from
                    a vivid dream as having actually happened.
       
                      svnt wrote 11 hours 57 min ago:
                      It has fallen out of favor based on a lack of evidential
                      support, for sure. It has not really been dismantled
                      publicly scientifically, but mostly quietly, perhaps in
                      order to protect its practitioners, perhaps because the
                      research cannot currently be ethically conducted.
                      
                      I am not advocating for it, just stating the near total
                      lack of substantive scientific evidence presented either
                      in support or opposed.
       
            bigbuppo wrote 16 hours 39 min ago:
            I forgot what I was going to type, but I didn't get enough sleep
            last night.
       
            jyounker wrote 16 hours 59 min ago:
            Are you sure about that?
       
            DenisM wrote 17 hours 3 min ago:
            Cleanup is an LRU process.
            
            Once a memory lapses you have to relearn from life experience (or
            not at all).
       
              thaumasiotes wrote 13 hours 28 min ago:
              No, a lapsed memory can be provoked. It doesn't have to be
              relearned. It is "lapsed" because the organizational path to it
              within your brain has been lost, like a book in a library that
              has been left out of the card catalog, but just like the book, if
              you happen to find it anyway, it will be there.
              
              Compare, from [1] :
              
              > at the first news of English ships in the area, Buckley rushed
              to the spot. He attempted to make contact, but couldn’t swim
              out to the ship and couldn’t convince the ship to send a boat
              to him (Buckley had, at this point, forgotten how to speak
              English.) Buckley was again heartbroken until another ship showed
              up, and he found the English colonists and tried to approach
              them:
              
              > “Presently some of the natives saw me, and turning round,
              pointed me out to one of the white people; and seeing they had
              done so, I walked away from the well, up to their place, and
              seated myself there, having my spears and other war and hunting
              implements between my legs. The white men could not make me
              out–my half-cast colour, and extraordinary height and figure
              [Buckley was around 6’5” or taller,]–dressed, or rather
              undressed, as I was–completely confounding them as to my real
              character. At length one of them came up and asked me some
              questions, which I could not understand; but when he offered me
              bread–calling it by its name–a cloud appeared to pass from
              over my brain, and I soon repeated that, and other English words
              after him. …
              
              > “Word by word I began to comprehend what they said, and soon
              understood, as if by instinct, that they intended to remain in
              the country; that they had seen several of the native chiefs,
              with whom–as they said–they had exchanged all sorts of things
              for land; but that I knew could not have been
              
              I submit that it takes more than a day to learn English if you
              don't already know it.
              
              Once I was in a Toys-R-Us and noticed a cover image among the
              bottom-of-the-barrel DVD display which caused me to put what I
              was doing on hold for several minutes while I stared at the DVD.
              I bought it, and it turned out to be a movie I had watched many
              times when I was very young, but that information hadn't been
              accessible to me.
              
  HTML        [1]: https://evolutionistx.wordpress.com/2016/12/16/anthropol...
       
        cyberdrunk2 wrote 17 hours 22 min ago:
        I wonder if this could help explain why creatine helps mitigate the
        effects of sleep deprivation. Since creatine aids in water retention.
        
  HTML  [1]: https://pubmed.ncbi.nlm.nih.gov/16416332/
       
          Citizen8396 wrote 14 hours 43 min ago:
          I would imagine it has more to do with its principal function in
          recycling ADP back to ATP (fuel for cells). People who are sleep
          deprived also have impaired glucose metabolism, meaning that the
          cellular "fuel pipeline" is impeded. Perhaps creatine is especially
          helpful under these conditions.
          
  HTML    [1]: https://pmc.ncbi.nlm.nih.gov/articles/PMC1991337/
       
          jorvi wrote 17 hours 2 min ago:
          Mix your cheap instant coffee with creatine powder and ORS for that
          ultimate early morning flavor bomb!
       
            huemaahn wrote 15 hours 38 min ago:
            Welp, now I’m bout to make the nastiest coffee known to man for
            the next 3 months
       
            pawelduda wrote 15 hours 42 min ago:
            Don't forget to intensely shake your head after consumption for a
            proper brain flush
       
            zer00eyz wrote 15 hours 52 min ago:
            The mechanism of creatine isn't that straight forward.
            
            You need to take it for a while for it to build up, and for water
            to accumulate in cells.
            
            It would also be disgusting in a cup of coffee!
       
          layer8 wrote 17 hours 20 min ago:
          It’s not clear how water retention would help with the needed
          flushing.
       
            regularfry wrote 17 hours 16 min ago:
            Hypothetically, more water retention would mean that the fluid
            being flushed is less concentrated, and if the flushing mechanism
            is triggered by a certain concentration level then it'll happen
            less frequently.
            
            Hard to imagine that it would be worth more than a few percent
            though.
       
              layer8 wrote 17 hours 14 min ago:
              Less flushing sounds like it would also worsen the sleep
              deprivation, even if it reduces the momentary lapses.
       
        kurisufag wrote 17 hours 24 min ago:
        anecdotally, i never feel better than when i haven't slept. spent 8pm
        tuesday -- 8pm thursday this week awake nursing cheap energy drinks,
        and not only could i manage a higher-than-usual level of focus, i was
        genuinely content.
        
        bombed a midterm halfway though, but at least i felt good about it.
       
          boogieknite wrote 16 hours 35 min ago:
          anecdotally i feel pretty good when im buzzed but reality is my
          performance is impaired. there is a teeter-totter of overconfidence
          and impairment where the liquid confidence actually helps more than
          the impairment impairs but its a sweet spot
       
            kurisufag wrote 16 hours 5 min ago:
            sleep deprivation definitely reduces raw reasoning ability. in some
            cases, though (and this is true for getting buzzed as well) the
            trade-off is absolutely productive.
       
          rtaylorgarlock wrote 17 hours 14 min ago:
          Age sounds like a factor here. I know zero long-term healthy ppl in
          30s and beyond who act/think this way.
       
            jtuple wrote 14 hours 21 min ago:
            I've done a few all-nighters in my 30s and 40s, and they generally
            feel the same as my 20s. Still get that clear headed, high focus
            second wind around 4am that carries through until noon or so.
            
            But, I definitely crash harder than I did in my 20s and need longer
            to recover after. In my 20s, would be fine if the next night was a
            normal one, now it takes multiple days.
            
            It's definitely something I try to avoid at this age, as opposed to
            just being standard procedure back in college.
       
            freedomben wrote 17 hours 1 min ago:
            Indeed, as a 20 year old I would stay up all night pretty regularly
            for work and occasionally fun.    At 40 I'm not sure I would live
            through it, at least not in a cognitive state where I could
            converse.
       
          puzzlingcaptcha wrote 17 hours 14 min ago:
          It's not unusual to feel good after pulling an all-nighter. Sleep is
          when re-uptake of serotonin takes place, so if you interrupt it you
          end up with a surplus. Although there are also other possible
          explanations [1] 1.
          
  HTML    [1]: https://www.pnas.org/doi/10.1073/pnas.2214505120
       
            taeric wrote 15 hours 57 min ago:
            I'm assuming it is similar to the "runners high" people get at the
            end of a long run?  You will feel very energized in ways that don't
            make sense.  And if you don't force yourself to just lay down and
            pass out, you can keep going for longer than you would have
            thought.  Will crash harder, though, if my experience is common.
       
          90ne1 wrote 17 hours 15 min ago:
          I see the same thing in myself.
          
          I've attributed it to a my brain moving to power-saving mode and
          muting some of my anxiety / perfectionism tendencies. Does this
          explanation resonate with you at all?
       
            kurisufag wrote 16 hours 13 min ago:
            That's possible. It feels a lot like the placebo component in
            drinking: if you're free to ignore one of the few things you need
            to /live/, it should be much easier psychologically to be carefree
            (similar to "oh, haha, i'm drunk, might as well get wacky").
       
          jcims wrote 17 hours 17 min ago:
          I've got pretty bad ADHD and I find that my mind is more quiet,
          focused and productive on mornings after a night of 2-4 hrs of sleep
          than it has ever been on meds or anything else.  It all falls apart
          by the afternoon, but for a while it's a nice feeling.
       
          barrenko wrote 17 hours 17 min ago:
          Well, not sleeping through the night, you'll feel genuinely euphoric
          around dawn, it's one of the most immediate "cures" for clinical
          depression.
       
        paglaghoda wrote 17 hours 40 min ago:
        Rest in peace to all the college dudes covering the whole syllabus
        within 24 hours of the exam
       
          znpy wrote 16 hours 40 min ago:
          Not a college dude, but i used to work on shits (including night
          shifts) and adjusting to and from a five-nights (23:30-07:30) shift
          isn’t that pleasant either.
       
            nfriedly wrote 14 hours 40 min ago:
            I think you meant to say "...I used to work on shifts..."
            
            That, or maybe try a laxative.
            
            (Man, if ever there was a time I wanted emoji support on HN, this
            is it!)
       
          wslh wrote 17 hours 36 min ago:
          It is always great to follow the instructions from a psychiatrist [1]
          
  HTML    [1]: https://thelastpsychiatrist.com/2007/08/how_to_take_ritalin_...
       
            thesmtsolver wrote 15 hours 39 min ago:
            This is just outdated, bad and dangerous  advice that a ton of
            recent research invalidates.
            
            1. Ritalin, and other stimulants are not cognition enhancing for
            non-ADHD adults and may in fact do the opposite. [1] 2. > Because
            the doctor will rigorously apply artificial and unreliable
            diagnostic categories backed up by invalid and arbitrary screens
            and queries to make a diagnosis.  So after this completely
            subjective and near useless evaluation is completed, your doctor
            should be able to exercise prudent clinical judgment to decide if
            Ritalin could be of benefit.
            
            What else can you do for psychiatric conditions? We don't have a
            magic ADHD-o-meter but know that it statistically impacts lifespan,
            health, etc. Even for more objective measures like blood glucose,
            BP, BMI, clinical interventions are based on discrete thresholds
            that don't exist in nature.
            
  HTML      [1]: https://www.cam.ac.uk/research/news/smart-drugs-can-decrea...
       
            plmpsu wrote 17 hours 26 min ago:
            I miss her.
       
              MarcelOlsz wrote 16 hours 8 min ago:
              What happened? Did they pass or something or just stop posting or
              what?
       
                _--__--__ wrote 10 hours 16 min ago:
                TLP was doxxed in a way that threatened their real life
                psychiatry practice, briefly blogged on Tumblr under a
                different psuedonym, and has since had little online presence
                other than rare tweets and randomly dropping a self-published
                book on Amazon (_Sadly, Porn_ by 'Edward Teach').
       
        jongjong wrote 17 hours 40 min ago:
        Good to know that the brain finds a way to flush itself while awake. I
        think I've become pretty good at putting unused parts of my brain to
        sleep while awake. My brain is like that of a dolphin now.
        
        But on rare occasions (like a couple of times a year), I get migraine
        auras and stuff disappears from my field of view. Can last about an
        hour. I feel like that's my visual cortex falling asleep.
       
        ferguess_k wrote 17 hours 48 min ago:
        I wonder if a 30-min nap improves the situation. But I need to tell the
        brain to hold the flushing until the nap.
       
          gwbas1c wrote 16 hours 16 min ago:
          > I wonder if a 30-min nap improves the situation.
          
          I pretty much wait until I feel drowsy, and then take a 15-30 minute
          nap
       
          JKCalhoun wrote 16 hours 49 min ago:
          Anecdotally, it seems to. I have laid down and closed my eyes even
          for a short while. And believe that I have even had a "flushing"
          sensation, that feels like a mental fog being lifted (or "drained", I
          guess).
          
          I pop up 5 minutes later and feel completely refreshed.
       
            256_ wrote 11 hours 34 min ago:
            I do something similar, although there's an added peculiarity when
            I do it. I lie down for 5 minutes and wake up 9 hours later.
       
            assimpleaspossi wrote 14 hours 17 min ago:
            Agree though it's 10 minutes for me.
            
            When I owned some property out in the country, it was a 2 1/2 hour
            car trip to get there. Sometimes I just couldn't finish the drive
            home but pulling over to the side of the road for a 10-minute nap
            made me feel fully refreshed.
       
            ferguess_k wrote 15 hours 27 min ago:
            I had the same experience. The only trick is to keep it short, like
            5-10 minutes. Any longer and the nap may bring negative impacts.
       
            nullstyle wrote 16 hours 22 min ago:
            Fwiw, i have the opposite experience of napping.  Napping adds to
            mental fog for me especially for the hour immediately after
            napping. Its not until several hours later that i actually
            experience any loss of mental fog or increase in clarity.
       
              g-b-r wrote 15 hours 24 min ago:
              It probably depends on how much sleep you're lacking, and how
              long the nap is.
              
              My experience after sleeplessness nights is that even few seconds
              help significantly, especially when you're almost unable to
              function anymore.
              
              If the nap lasts longer than 30 minutes, though, you have a good
              chance of feeling groggy afterwards.
       
          rtaylorgarlock wrote 17 hours 13 min ago:
          There's controversy over exact mechanisms involved in glymphatic
          function, so suffice it to say that allegedly even just NSDR / yoga
          nidra will engage a rest deep enough for glymphatic function to
          engage/improve
       
            DenisM wrote 16 hours 56 min ago:
            I was disappointed the article didn’t mention that. Can you give
            me some pointers. I will use Google but HN curated content is often
            a better starting point. :)
       
        cdelsolar wrote 17 hours 54 min ago:
        I slept around 5 hours last night split up into two periods because my
        baby daughter woke up crying from fever and wanted to play / was
        hallucinating / etc. She's totally fine now but I am wondering if there
        is a correlation between dementia and having kids.
       
          freedomben wrote 16 hours 59 min ago:
          Ah, those days were the absolute grinder for me.  How a precious and
          sweet little baby girl can become an absolute monster all night long,
          and then wake up the next day back to her normal self while leaving
          me a hollowed out mess of a human is a mystery for science to solve
          someday.
       
            cdelsolar wrote 15 hours 21 min ago:
            aren't they the best though? but yeah, back to the grind, and now i
            also have her respiratory disease and am trying to launch my
            startup off the ground ...
       
          aliljet wrote 17 hours 16 min ago:
          What have you done when your toddler wakes up at random hours during
          the night to interrupt your sleep and come and play? That's what has
          truly obliterated our sleep. Everything else was a passing fad that
          was minimally painful at best..
       
          zoeysmithe wrote 17 hours 16 min ago:
          I mean the baby stage doesn't last very long. I dont even remember
          the sleepless nights from my own kids anymore lol
          
          Chronic sleep deprivation is the larger issue. And how we really
          don't have treatments on how to fix that, and how ultimately sleep
          phase issues are a social issues (being forced to follow a fixed
          modern schedule). Not to mention how closely that's tied to ND
          people. So a lot of us deal with sleep issues since we were little,
          but work and school dont give us the flexibility we need. For
          example, flex hours could be helpful here. I would rather work 10am
          to 6pm or  11am to 7pm most days. Or 5-6 hours during the day and 2-3
          hours late at night.
       
            randerson wrote 15 hours 33 min ago:
            I suffered chronic insomnia most of my life and seen my fair share
            of experts and read a few books about it. There are definitely
            treatments for the majority of insomniacs.
            
            Sleep deprivation is often caused by alcohol, inconsistent
            sleep/wake times, high color temperature lighting (>3000K) in the
            hours before bed, failure to spend time outdoors in natural light
            in the morning, temperature too warm (68F is ideal), caffeine (or
            other stimulants) in the afternoon, associating the bedroom with
            tasks other than sleep and sex, or simply spending too much time in
            bed.
            
            Following doctor's advice for the last one: Start by going to bed
            at, say, 1am and waking up at 6am. Follow this without fail for a
            few weeks. You'll be exhausted but keep at it. Eventually you
            should find yourself falling asleep quickly. If you wake up
            exhausted, pull back bedtime by 10 minutes. Do this for a week.
            Rinse and repeat until you are waking up at 6am refreshed. That is
            how you determine how many hours your body needs to sleep, and how
            long you should be in bed. Helped me.
       
              zoeysmithe wrote 14 hours 46 min ago:
              I'm autistic with delayed sleep-wake cycle. For autistics DSWPD
              is pretty common. There's just no fixing that for the vast
              majority of us, we're just expected to follow strict schedules
              and if we are underslept, too bad for us.
              
              ND people get this pretty badly. 2023 study: The incidence of
              sleep problems in ASD patients ranges from 32 to 71.5%,
              especially insomnia, while an estimated 25–50% of people with
              ADHD
              
              Insomnia is different, but tbf, insomnia for many people can't be
              treated well or if not at all. CBT is helpful if you look at the
              studies and ignore the follow up studies showing relapses between
              40-70%. We can stuff people with melatonin and hypnotics but
              after a while that no longer works. So looking at this, it looks
              like things like drugs and CBT can help 70% of insomnia sufferers
              but the relapse rate is as high as 70%, so we're looking at
              people who can actually be cured as low as 15-20% of total
              insomnia sufferers.
              
              Its not caffeine or screens for us, its just how the machinery of
              the human body works. This is like telling a depressed person to
              just 'cheer up.' I'm glad that worked for you, but your story is
              just an anecdote, and the science for this is still pretty dismal
              unfortunately.
              
              The science can't work because at this point we're going against
              our nature. A lot of people cannot subscribe to a modern
              industrialized sleep schedule because its not natural for us to
              have extremely strict sleep and wake times.
       
                randerson wrote 8 hours 52 min ago:
                Thanks for elaborating. I have an autistic child, and you
                might've just explained why my kid has more energy at night
                than during the day. She tends to fall asleep around midnight
                (but at least gets a solid 8 hours of sleep from there). We're
                lucky to have a school with a late start time.
       
            chasebank wrote 17 hours 7 min ago:
            "Chronic sleep deprivation is the larger issue. And how we really
            don't have treatments on how to fix that"
            
            Sure we do, however, not everyone is willing to hike 20-30 miles a
            day and sleep in a tent. It's not practical but it is very
            effective.
       
              zoeysmithe wrote 17 hours 5 min ago:
              Physically exhausting yourself isnt a solution. Its tangential to
              the real issue. Its a bit like suggesting you can solve anxiety
              caused by trauma by drinking large amounts of alcohol everyday.
              No, instead we should be treating trauma. Its like putting
              autistic kids through rough ABA therapy, no instead we should
              finding accommodations and support for autistic people.
              
              People have natural sleep rhythms. Society should conform to
              that, instead capitalism demands we conform to what it deems
              profit maximizing.
       
                sureglymop wrote 14 hours 39 min ago:
                I agree with you. I regularly have strong insomnia and I have
                tried physical exhaustion.
                
                It usually works for the first few days of doing it but then
                it's like my body (probably moreso my mind) gets used to it and
                it doesn't help with sleep anymore.
                
                Arguably it feels even more unhealthy because it's like my body
                is fully exhausted and tired but my mind won't let me sleep so
                no restoration can happen.
       
                chasebank wrote 17 hours 0 min ago:
                Not physically exhausting yourself is the real issue. It's our
                natural state as humans. We're not meant to be staring at
                screens having discussions about chronic sleep deprivation on
                an internet forum, we're meant to be outside moving our bodies.
       
          Mizza wrote 17 hours 23 min ago:
          Memory loss from sleep deprivation is an evolutionary advantage. If
          you remembered how rough the first few months of new children are,
          you wouldn't do it again.
       
          debo_ wrote 17 hours 42 min ago:
          This kind of fear is a quick route to insomnia. One of the most
          effective ways to reduce sleep is to worry about it.
       
            grumpy-de-sre wrote 17 hours 28 min ago:
            And when that happens, of course HN has the answer
            
  HTML      [1]: https://news.ycombinator.com/item?id=15997016
       
              debo_ wrote 17 hours 14 min ago:
              I think CBTI is pretty horrible but I'm happy it works for some
              people.
              
              There's so much helpful stuff out there now it's rather a
              blessing.
       
          sarchertech wrote 17 hours 44 min ago:
          I’m on my 3rd (she’s 1 week old today) at 42. With the first 2 it
          was only terrible for the first couple months. Once I just got used
          to going to sleep at 9:30 I was mostly fine.
       
            grumpy-de-sre wrote 17 hours 32 min ago:
            We're expecting our first in a few months.
            
            NGL I'm low key wondering if my messed up natural rhythm of 9pm-4am
            is going to be potentially handy.
       
              Tade0 wrote 16 hours 52 min ago:
              As a father of two I would say "nope", primarily because you
              won't be deciding the rhythm. Best you can do is coordinate sleep
              with your partner so that there's at least one somewhat
              functioning parent at all times.
              
              As I'm typing this my 1.5yo is napping. I had maybe 6h of sleep
              but I'm after (part time) work and at home already, so I should
              probably nap as well.
              
              Can't. My adult body won't go to sleep right now even though I'm
              feeling drowsy because it's too bright, too loud and chiefly I
              already had too much caffeine in the morning and I have like 15
              minutes until I'll have to head out to collect my older child
              from preschool.
              
              My SO is knocked out cold at the moment though, so I'll be
              relying on her this evening.
       
              zurichisstained wrote 17 hours 2 min ago:
              I have a similar natural rhythm, or I should say "had". For the
              first year, especially the first few months, it was a godsend
              (for my wife, especially), but now that we're in a fairly
              consistent sleep routine with our two year old (~8pm-7am), I've
              shifted to something more like 8pm-1am out of necessity.
              
              Although... I was up until 4am and got up at 6:30am and feel
              surprisingly great, so it still happens from time to time. :)
       
            micromacrofoot wrote 17 hours 36 min ago:
            Yeah that's the trick, sleep asap
       
          arethuza wrote 17 hours 47 min ago:
          I remember this quote from when we had young kids:
          
          "Insanity is hereditary. You can get it from your children."
          
          And then as soon as they are in their 20s and reasonably self
          sufficient we had to get a puppy to keep me sane!
       
            spockz wrote 17 hours 44 min ago:
            Long days and short years.
            
            Did you have empty nest syndrome?
       
              arethuza wrote 17 hours 28 min ago:
              More like empty head syndrome - but getting a dog was the best
              thing I've done in years.
       
          aethrum wrote 17 hours 47 min ago:
          Probably negatively correlated cause you have someone to interact
          with in your old age/better chance of community :)
       
            skeeter2020 wrote 16 hours 29 min ago:
            Also I think of (hopefully at least one of) my three kids as a
            diversed retirement portfolio :)
       
        rtaylorgarlock wrote 18 hours 9 min ago:
        Long live healthy sleep for brain health, and thank goodness light
        exercise helps this same glymphatic system.
       
          cestith wrote 14 hours 21 min ago:
          ISTR that light exercise also helps with quality of sleep.
       
            HPsquared wrote 11 hours 38 min ago:
            It stands to reason.
       
              stOneskull wrote 10 hours 29 min ago:
              It lays to drain.
       
       
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